Hemp seed oil and CBD oil are not the same, so how is hemp seed oil different from CBD Oil? Hemp seed oil is not a suitable alternative for CBD. The seeds of the cannabis plant are used to make hemp seed oil. Hemp seeds are rich in Omega-6 fatty acids and phytonutrients but contain no active cannabinoids or terpenes. The leaves and flowers of the hemp plant are used to make CBD oil. They are rich in phytonutrients, terpenes, and other medicinal compounds. All CBD oils are made from hemp flowers and leaves. Some companies mix hemp seed oil with CBD oil, but the active ingredients are only in the flower and leaf extracts.